Quantification of 6-gingerol in Zingiber officinale extract, ginger-containing dietary supplements, teas and commercial creams by validated HPTLC densitometry
نویسنده
چکیده
A sensitive and accurate high-performance thin layer chromatography (HPTLC) method has been developed to determine the quantity of 6-gingerol in the methanolic extract of Zingiber officinale containing dietary supplements, teas and commercial creams. 6-gingerol was separated on aluminumbacked silica gel 60 F254 plates with n-hexane:ethyl acetate 40:60 (%, v/v) as mobile phase. A compact band was obtained for 6-gingerol at Rf value of 0.33±0.04. The calibration plot was linear in the range of 50-1000 ng/spot of 6-gingerol and the correlation coefficient of 0.995 was indicative of good linear dependence of peak area on concentration. The developed HPTLC densitometric method was found cheap, selective, precise and accurate, and can be used for routine analysis of gingers in the quality control laboratories of herbal drug industries.
منابع مشابه
High Performance thin layer Chromatographic Analysis of 10-Gingerol in Zingiber officinale Extract and Ginger-Containing Dietary Supplements, Teas and Commercial Creams
Ginger rhizome powder is widely used as a food spice and an herbal medicine around the world. A sensitive and accurate High Performance thin layer chromatographic (HPTLC) method has been developed to determine the quantity of 10-gingerol in Zingiber officinale extract and ginger-containing dietary supplements, teas and commercial creams on aluminum-backed silica gel 60 F254 plates with n-hexane...
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